The aim of this project is to establish a grant scheme to fund projects that aim to improve the identification and management of atrial fibrillation (to prevent stroke), with a focus on service evaluation, medical education and quality improvement projects. The Network of AHSNs and the BMS-Pfizer alliance will jointly issue a Request for Proposals (RFP) that describes the clinical practice areas that they hope to address with available grant funding. Successful applications should aim to meet such identified clinical gaps and must comply with clause 19 of the ABPI Code of Practice (Medical and Educational Goods and Services).

We welcome submissions from Academic Health Science Network (AHSN) from across the country, including similar organisations within Scotland, Wales and Northern Ireland. The applications will be reviewed by an independent panel including experts within the field.

The deadline for applications is the 17th of May (midnight, UK GMT) and we will notify successful grant awardees by the end of June 2019.


Further information on the application and/or submission process can be found in the Request for Proposal document. If you have questions regarding this, please direct them in writing to the Grant Officer Jo Harbron with the subject line “UK-AF stroke reduction”.

This programme has run in 2016, 2017 and 2018 (project summaries can be found below) and it would be expected that projects submitted in 2019 would not overlap significantly or repeat those that were funded in previous years. Magnification/expansion of previously successful quality improvement programmes in these therapy areas would be considered within scope.

2018 IGLC

Oxford AHSN

The project will establish a network of Local Anticoagulation Champions across 43 GP practices in Berkshire West CCG. The champions will receive intensive training from secondary care specialists and patient leaders to upskill them to the point where they can become ‘local experts’ within their practice thereby increasing the capability of primary care to safely and effectively prescribe anticoagulation therapy for patients at risk of an AF related stroke. Simultaneously, a virtual MDT will be established which will provide specialist secondary care advice with open access for local GPs to enable rapid access to advice for the most complex patients.

Innovation Agency West Coast

The overall goal of the project is for Healthy Living Pharmacies (HLP) in the community, to support practice based pharmacists in primary care in improving monitoring for patients with AF and the ultimately prevent AF related strokes. We plan that community pharmacists (HLPs) will identify and monitor patients with atrial fibrillation to improve outcomes in these patients, by using technology and services in innovative ways such as sending text messages and using a mobile ECG in the pharmacy. This project will extend the community pharmacist role to work with GP practice pharmacists to support the identification and management of AF. HLPs will support approximately 30 GP practices, and pharmacies in two of our most deprived boroughs of Knowsley and Halton, in Cheshire and Merseyside. It will use a combinatorial approach of innovative technology to support the management and engagement of patients.

Health Innovation Network

This project will address unmet need in the diagnosis and management of AF for older adults with additional needs, defined as those over the age of 65 years who are housebound, in nursing homes or in residential care or with complex care needs due to other issues, such as dementia or frailty. This patient group frequently receives suboptimal care because of the specific challenges in confirming an AF diagnosis and in delivering optimal treatment, in particular warfarin and the associated monitoring of INR.

2017 IGLC

AF Advance Programme East Midlands

Since April 2013, quality improvement projects carried out in the East Midlands has increased the number of patients diagnosed with AF and also improved the rate of high-risk AF patients being treated with anticoagulation. This project aims to further these improvements in Primary Care by utilising AliveCor Kardia mobile devices to increase AF detection rates, reduce number of undiagnosed AF patients and provide effective anticoagulation in newly diagnosed patients.

Wessex AHSN


“There are 10% more people aged over 65 year within the Dorset CCG than national average, this increases the likelihood of Atrial Fibrillation and therefore the risk of stroke. With the introduction of direct oral anticoagulants (DOACs), some in Primary Care may benefit from support when discussing choices of anticoagulation therapy with patients. The aim of the project is to empower Primary Care clinicians (including pharmacists) by improving their knowledge and skill. Therefore, lead to increased identification and review of AF patients, as well as be in the position to counsel them for the most suitable therapy.”


Imperial College NHS Trust

There is a median 3% per annum risk of stroke at the time of diagnosis of AF. This project recognise the importance of initiating anticoagulation at the earliest possible opportunity post diagnosis by establishing a community based system for identification, triaging and early risk management. Patients at risk of AF or those with symptoms suggestive of AF are given smart phones equipped with AliveCor devices. The results are fed back to a centralised team where the ECG findings are managed accordingly to predefined protocols. The aim is also for the centralised team to be the first point of contact for Primary Care clinicians and will provide necessary up-skilling of GPs.

Royal Brompton and Harefield NHS Foundation Trust

Community pharmacists currently provide advanced services such as Medicines Use Reviews and New Medicine Service. They therefore not only have the skills but are ideally situated to facilitate AF diagnosis and management.

In this project 30 community pharmacies in the Hillingdon area will aid AF detection by identifying patients aged over 65 years with AF associated risk factors and undertaking an ECG using the Kardia monitor. Anyone who is found to have undiagnosed AF and is not appropriately anticoagulated or those with diagnosed AF with a high symptom burden or problems with anticoagulation will be referred to the Arrhythmia Care Team at Harefield Hospital for prompt management.

2016 IGLCs

Innovation Agency North West Coast

Lancashire has one of the highest rates of Atrial Fibrillation (AF) related strokes within the UK. One of the main contributing factors is the number of undetected AF patients and a poor rate of anti-coagulation control in those that have been identified with AF.

The goal of this project is to reduce and prevent strokes secondary to AF by optimising existing AF pathways and integrating innovative technologies, such as genotype-guided dosing and use of devices to support self-monitoring, which include digital integration to the GP or hospital systems from the patient via an App, automated phone call or web portal.

This project aims to match the right patient with the most suited anticoagulation therapy, empower patients, optimise staff time and allow easy data sharing and reduce the financial burden of strokes on the NHS.

Cambridge University Hospitals NHS Foundation Trust

Studies carried out from 2012 onwards showed that nearly half the patients admitted with AF were not anticoagulated. In response to this, the SOS-AF project was created focusing on stroke prevention by introducing a specialist service consisting of stroke consultants, registrars and specialists nurses. By supporting both primary and secondary care (inpatient and outpatient) services, the aim is to increase AF detection within the area, offer risk stratification and appropriate management of anticoagulation.

AHSN North East and North Cumbria (NENC)

There are over 3,000 people with undiagnosed Atrial Fibrillation (AF) in the Newcastle Gateshead CCG area, and a third of people who suffer a stroke are known to have AF, but are not taking any form of anticoagulation. This project aims to optimise the AF anticoagulation pathway in Newcastle with the introduction of three innovations: warfarin sensitivity genotype testing before choice of anticoagulant is made, then where appropriate, genotype guided warfarin initiation, and subsequently an option for patients to self-test their INR at home.

Oxford Academic Health Science Network

The provision of anticoagulation therapy is primarily managed within General Practice, where there are well-known demand and recruitment pressures. In order to reduce the burden, the project is introducing a novel model of anticoagulation where a Specialist Pharmacist works with the patient to decide on appropriate anticoagulation and prescribe the first month’s therapy. The model also provides consistency in prescribing, as the team of Specialist Pharmacists will be working to defined anticoagulation guidelines

Sandwell and West Birmingham Hospitals NHS Trust

Data from NHS England for the Black Country STP data pack showed that in 2016, premature death from stroke is worse than national average. The project aims to incorporate evidence-based education, improve the quality of AF diagnosis, treatment and management. These are done through up-skilling mainly primary care clinicians but also secondary care clinicians, use of mobile detection devices (AliveCor) and implementation of pathway changes. The project also utilises a multimedia information-sharing platform to provide Primary Care clinicians further support from specialists.